2011年1月14日金曜日

Functional specialization within the dorsolateral prefrontal cortex: a review of anatomical and physiological studies of non-human primates.

Neurosci Res. 2006 Feb;54(2):73-84.
Hoshi E.

Dorsolateral prefrontal cortex (DLPFC)についてのレビュー論文
dorsal DLPFC (DLPFCd)とventral DLPFC (DLPFCv)の違い

・解剖学的構造(Fig.2が分かりやすい)
DLPFCdとの接続:cingulate cortex, PMd, PG (posterior parietal cortex) and PGm (posterior parietal cortex).
DLPFCvとの接続:Insular cortex, PMv, PF (posterior parietal cortex) and PFG (posterior parietal cortex).
DLPFCdは小脳と強い接続(DLPFCvと小脳の接続はさほど強くない)

・機能
encoding:
spatial information ( ← posterior parietal cortexとの接続ありとconsistent).
object identity,expected or obrained reward,a sequence of spatial motor acts,collective evidence over time,response outcome,action strategies (repeat-stay/change-shift)
( ← prefrontal内部,parietal,inferior temporal cortexとの接続ありとconsistent).

DLPFCd: motor planning, phases in multiple-step tasks and memorizing spatial locations or goals.
→ representing processed motor information (such as arm use or target location), and integrating multiple classes of information for plannning action.

DLPFCv: visuo-spatial location of attended signals and visuo-spatial information about cues.
→ detecting visuospatial signal as the primary interface for sensory signals.

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