2011年2月4日金曜日

Prefrontal coding of temporally discounted values during intertemporal choice.

Kim S, Hwang J, Lee D.
Neuron. 2008 Jul 10;59(1):161-72.

Reward from a particular action is seldom immediate, and the influence of such delayed outcome on choice decreases with delay. It has been postulated that when faced with immediate and delayed rewards, decision makers choose the option with maximum temporally discounted value. We examined the preference of monkeys for delayed reward in an intertemporal choice task and the neural basis for real-time computation of temporally discounted values in the dorsolateral prefrontal cortex. During this task, the locations of the targets associated with small or large rewards and their corresponding delays were randomly varied. We found that prefrontal neurons often encoded the temporally discounted value of reward expected from a particular option. Furthermore, activity tended to increase with [corrected] discounted values for targets [corrected] presented in the neuron's preferred direction, suggesting that activity related to temporally discounted values in the prefrontal cortex might determine the animal's behavior during intertemporal choice.

サルの異時点間意思決定。 http://bit.ly/eHK9LF 選択行動は双曲割引で説明されて、前頭前野外背側部(DLPFC)のニューロンが割引現在価値を保持。しかし、Daeyeol Lee、相変わらず力技だなあ。

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