2011年9月15日木曜日

Differential roles of human striatum and amygdala in associative learning

Jian Li, Daniela Schiller, Geoffrey Schoenbaum, Elizabeth A Phelps & Nathaniel D Daw
Nature Neuroscience (2011)

Although the human amygdala and striatum have both been implicated in associative learning, only the striatum's contribution has been consistently computationally characterized. Using a reversal learning task, we found that amygdala blood oxygen level–dependent activity tracked associability as estimated by a computational model, and dissociated it from the striatal representation of reinforcement prediction error. These results extend the computational learning approach from striatum to amygdala, demonstrating their complementary roles in aversive learning.

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