2012年8月8日水曜日

Dopamine Enhances Model-Based over Model-Free Choice Behavior


Klaus Wunderlich, Peter Smittenaar, Raymond J. Dolan
Neuron, Volume 75, Issue 3, 418-424, 9 August 2012

Decision making is often considered to arise out of contributions from a model-free habitual system and a model-based goal-directed system. Here, we investigated the effect of a dopamine manipulation on the degree to which either system contributes to instrumental behavior in a two-stage Markov decision task, which has been shown to discriminate model-free from model-based control. We found increased dopamine levels promote model-based over model-free choice.

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